Drinking apple cider from a specific cider mill in Massachusetts was statistically associated with E. coli O157:H7 infection. Fortunately the number of contaminated lots of apple cider were small. Cultures of ten cider containers purchased from the cider mill throughout the fall did not show the presence of E. coli O157:H7. The cider-press operator also raised cattle. Manure samples from the cattle also did not show the presence of E. coli O157:H7. There was no evidence that farm workers had recent E. coli O157:H7 infection.