In April 2013 an outbreak of Cryptosporidiosis occurred among emergency responders to a tractor-trailer rollover. On March 10, 2013 a truck carrying approximately 350 preweaned Holstein calves overturned in a snowstorm near Colby, Kansas. Because of the very young age of the calves and the injuries and stress resulting from the rollover, most calves that survived the crash has to be carried by responders onto cattle trailers. Six cases of cryptosporidiosis were identified among 15 responders. Disease was associated with carrying calves and contact with fecal matter.