In June 2016, public health officials investigated an outbreak of Salmonella Anatum infections involving 32 patients residing in 9 states. Illness onset dates ranged from May 6-July 9, 2016. Eight people were hospitalized. There were no deaths. The outbreak strain was isolated from an imported Anaheim pepper. The combined epidemiologic, laboratory, and traceback evidence indicated that fresh hot peppers were the likely source of infection, but a single pepper type or source farm was not identified.