In October 2018 the CDC announced an outbreak of Salmonella Infantis infections associated with raw chicken products from a variety of sources. In interviews, ill people reported eating different types and brands of chicken products. The outbreak strain was identified in samples taken from raw chicken pet food, raw chicken products and live chickens. On February 21, 2019 the CDC stated the outbreak appeared to be over. Thirty two states reported 129 cases. Twenty five people were hospitalized. There was one death in New York. Illnesses started from January 19, 2018 to January 27, 2019.

In interviews, ill people answered questions about foods they ate and other exposures in the week before they became ill. Of 69 people interviewed, 60 people (87%) reported preparing or eating chicken products that were purchased raw. Ill people reported buying many different brands of raw chicken products from multiple stores. One person got sick after pets in their home ate raw ground chicken pet food. Two people lived with someone who works in a facility that raises or processes chicken.

WGS analysis of Salmonella bacteria isolated from 97 ill people and 139 food and environmental samples predicted resistance to some or all of the following antibiotics: ampicillin, chloramphenicol, ciprofloxacin, fosfomycin, gentamicin, hygromycin, kanamycin, nalidixic acid, streptomycin, sulfamethoxazole, tetracycline, and trimethoprim sulfamethoxazole.