In April 2019 public health officials announced a multistate outbreak of Escherichia coli O103 infections. Preliminary epidemiologic information suggests that ground beef is the source of this outbreak. On June 19, 2019 the outbreak appeared to be over. In total 209 people infected with the outbreak strain had been reported by 10 states: Florida, Georgia, Illinois, Indiana, Kentucky, Minnesota, Mississippi, Ohio, Tennessee, and Virginia. Twenty nine people had been hospitalized. Two cases of hemolytic uremic syndrome were reported. There were no deaths. Illnesses started on dates from March 1, 2019 to May 1, 2019.

Ill people in this outbreak ate ground beef from many sources. Some ground beef was recalled but investigators were not sure if all producers had been identified. On April 24, 2019 Grant Park Packing in Franklin Park, Illinois recalled approximately 53,200 pounds of raw ground beef products. K2D Foods, doing business as Colorado Premium Foods in Carrollton, Georgia recalled approximately 113,424 pounds of raw ground beef products on April 23, 2019.