On June 28, 2019 the CDC announced an outbreak investigation of Salmonella Uganda infections linked to consumption of fresh, whole papayas imported from Mexico.

On September 12, 2019 the outbreak was declared over. In total 81 outbreak associated cases were reported by 9 states. Twenty seven patients were hospitalized. There were no deaths. Illnesses started on dates ranging from January 14, 2019 to July 16, 2019.

Whole genome sequencing analysis of 66 bacterial isolates from ill people predicted antibiotic resistance to streptomycin and sulfisoxazole. Testing of four clinical isolates using standard antibiotic susceptibility testing methods by CDC’s National Antimicrobial Resistance Monitoring System (NARMS) showed one isolate with resistance to streptomycin and three isolates with no resistance. This resistance does not affect the choice of antibiotic used to treat most people.

Epidemiologic evidence and early product distribution information indicate that Cavi brand whole, fresh papayas imported from Mexico and distributed by Agroson's LLC was the likely source of the outbreak.