As part of an investigation of a salmonellosis illness investigation, Texas Department of State Health Services collected a bottle of rattlesnake pills from a patient's house. The pill samples tested positive for Salmonella Oranienburg. The Salmonella serotype isolated from the patient was not a genetic match by PFGE to that of the Texas patient. Investigators were not able to reinterview the patient.

Whole genome sequencing (WGS) indicated that the Salmonella isolated in the sample of rattlesnake pills was closely related genetically to an isolate from a patient in Kansas. The Kansas Department of Health and Environment reinterviewed the patient and learned that he had traveled to the State of Chihuahua, Mexico and purchased "pastillas de vibora de cascable" (rattlesnake pills). The patient believed the pills to be homemade and consumed five pills. There were no remaining pills for testing.