A cluster of Salmonella Enteritidis isolates were investigated in Minnesota. These were found to be indistinguishable by genetic subtype. The epidemiologic investigation implicated a restaurant. Illness histories and stool samples were collected from all restaurant employees. Sandwiches were the only menu item or ingredient significantly associated with illness. None of the restaurant employees reported gastrointestinal symptoms, however the same genetic subtype of Salmonella Enteritidis was identified in stool collected from two food workers. One of these food workers began work shortly before the first exposure occurred. This worker assisted with sandwich preparation and with other foods. The other food worker rarely, if ever, handled food. The restaurant did not have a glove use policy. There was no evidence of ongoing transmission after these food workers were kept from work.