An outbreak of Salmonella Enteritidis infections was associated with eating at four outlets of a restaurant chain in West Virginia. Isolates were sent to the CDC laboratory for MLVA (multi-locus variable-number tandem repeat analysis) testing and confirmed that at least 15 were identical. The epidemiologic investigation suggested that contaminated sausage was the source of the outbreak. There was evidence that the product may not have been cooked thoroughly prior to serving, and there was a likelihood of cross contamination. Product samples were collected but failed to show contamination; lot numbers could not be identified. Cases occurred in the counties of Logan, Putnam, Cabell, Boone, Wayne, Lincoln, and Fayette.